Hematopoietic cell transplantation in inborn errors of immunity - Part II: others
DOI:
https://doi.org/10.46765/2675-374X.2025v6n1e300Keywords:
Hematopoietic Stem Cell Transplantation, Primary Immunodeficiency Diseases, Wiskott-Aldrich SyndromeAbstract
Inborn errors of immunity (IEI) are a large, heterogeneous group of disorders resulting from deficiencies in immune system development and/or function, leading to increased susceptibility to infections, autoimmunity, autoinflammation, lymphoproliferation, and malignancy. Some diseases are classical hematopoietic cell transplantation (HCT) indications, such as Wiskott-Aldrich Syndrome, but more than 150 different IEI have been transplanted. Each disease and patient should be addressed individually as the clinical manifestations are variable, as well as the pre- and post-transplant care. This consensus strongly recommends that these patients are referred to experienced centers performing HCT for IEI.
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Copyright (c) 2025 Juliana Folloni Fernandes, Rafaella Muratori, Gisele Loth, Ana Karine Vieira, Paulo Klinger, Simone Franco, Carmem Bonfim
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