Vol. 7 No. 1 (2026): Journal of Bone Marrow Transplantation and Cellular Therapy

View Vol. 7 No. 1 (2026): Journal of Bone Marrow Transplantation and Cellular Therapy
Published: 01/08/2026

Letter to editor

  • Eurípides Ferreira: a pioneer of hematology and hematopoietic cell transplantation in Brazil

    Nelson Hamerschlak, Vicente Odone Filho
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e379

Original article

  • Outcomes of hematopoietic stem-cell transplantation in infants with KMT2A-rearranged acute lymphoblastic leukemia in first remission: a systematic review and single-arm meta-analysis

    Bianca Lisa de Faria, Áurea Maria Salomão Simão, Pedro Henrique Aquino Gil de Freitas, Ana Beatriz Bertol, Amanda Silva Gomes, Barkhá Vijendra, Beatrice Araujo Duarte, Lilian Maria Cristofani
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e345

  • The challenges in diagnosis and treatment of multiple myeloma in Latin America: a multinational survey and proposal for improvement

    Camila Peña, Breno Gusmão , Eloisa Riva, Alana von Glasenapp, Dorotea Fantl, Rodrigo Meneces, Aline Ramírez, David Gomez Almaguer, Julio Dámaso Fernández-Aguila, Manuel Antônio Granja, Esmedaly Romero, Jule Vasquez, Humberto Martinez-Cordero , Ariel Corzo, Rafael Cunha, Fernanda Lemos Moura, Maria Victoria Mateos
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e346

  • Effectiveness of therapeutic drug monitoring in patients undergoing allogeneic hematopoietic stem cell transplantation

    Joice Zuckermann, Bruno Mateus de Castro, Renata Garcia Ruschel, Lucas Bastos Beltrami, Rafaela Pivato da Fonseca, Priscila de Oliveira da Silva, Fernanda Fetter Scherer, Liane Esteves Daudt, Alessandra Aparecida Paz, Bibiana Verlindo de Araújo, Leila Beltrami Moreira
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e349

  • Current activity trends and outcomes of hematopoietic cell transplantation: A 2026 report from the Brazilian Registry of Hematopoietic Cell Transplantation in collaboration with the CIBMTR & SBTMO

    Anderson João Simione, Cinthya Corrêa da Silva, Afonso Celso Vigorito, Antonio Vaz Macedo, Heliz Regina Alves das Neves, Vanessa Aparecida do Nascimento Varjão, Monique Ammi, Flavia Ferreira da da Costa, Adriana Mendes de Quadros Cavilha, Alayne Magalhães T.D. Yamada, Vergilio Antonio Rensi Colturato, Phillip Scheinberg, Samir Kanaan Nabhan, Decio Lerner, Nelson Hamerschlak, Marcos Paulo Colella, George Maurício Navarro Barros, Alexandre Silvério, Adriana Seber, Simone Ojima Ferreira, Yana Augusta Sarkis Novis, Andreia Ribeiro de Almeida, Vanderson Geraldo Rocha, Maria Claudia Rodrigues Moreira, Claudia Caceres Astigarraga, Liane Esteves Daudt, Maria Cristina Martins de Almeida Macedo, Ricardo Chiattone, Juliana Folloni Fernandes, Volney Assis Lara Vilela, Rodolfo Daniel de Almeida Soares, Gustavo Machado Teixeira, Celso Arrais-Rodrigues, Roberto Luiz da Silva, Vaneuza Araújo Moreira Funke, Jayr Schmidt Filho, Vinicius Campos de Molla, João Samuel de Holanda Farias, Ricardo Pasquini, Carmem Maria Sales Bonfim, Abrahão Elias Hallack Neto, Rodolfo Froes Calixto, João Victor Piccolo Feliciano, Rafael Dezen Gaiolla, Marcelo Capra, Angelo Atalla, Milton Alexandre Ferreira Aranha, Rony Schaffel, Gianne Donato Costa Veloso, Fernando Sergio Blumm Ferreira, Andresa Lima Melo, Simone de Castro Resende Franco, Marcelo Alves Aduan, Andreza Alice Feitosa Ribeiro, Thiago Xavier Carneiro, Wellington Moraes de Azevedo, Giancarlo Fatobene, Abel da Costa Neto, Marcelo C. Pasquini, Mary E. Flowers, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e353

  • Current use and outcomes of cellular therapy: Brazilian Summary Slides – 2026

    Cinthya Corrêa da Silva, Anderson João Simione, Giancarlo Fatobene, Jayr Schmidt Filho, Adriana Seber, Nelson Hamerschlak, João Samuel de Holanda Farias, Vaneuza Araújo Moreira Funke, Phillip Scheinberg, Maria Claudia Rodrigues Moreira, Abel da Costa Neto, Vinicius Campos de Molla, Cilmara Cristina Kuwahara Dumke , Yana Augusta Sarkis Novis, Vanderson Rocha, Fernando Sérgio Blumm Ferreira, Volney Assis Lara Vilela, Grazielly Vargas Grilo, Andresa Lima Melo, Andreza Alice Feitosa Ribeiro, Marcos Paulo Colella, Afonso Celso Vigorito, Marcelo C. Pasquini, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e364

  • The Brazilian Data Managers Working Group: a 10-year grassroots initiative for the development of the national hematopoietic cell transplantation and cellular therapy registry

    Cinthya Corrêa da Silva, Heliz Regina Alves das Neves, Anderson João Simione, Alayne Magalhães Trindade Domingues Yamada, Antonio Vaz de Macedo, Afonso Celso Vigorito, Vanessa Aparecida do Nascimento Varjão, Flavia Ferreira da Costa, Adriana Mendes de Quadros Cavilha, Monique Ammi, Nelson Hamerschlak, Vergilio Antonio Rensi Colturato, Adriana Seber, Carmen Silvia Vieitas Vergueiro, Simone Ojima Ferreira, Andreia Ribeiro de Almeida, Vaneuza Araújo Moreira Funke, Ricardo Pasquini, Carmem Maria Sales Bonfim, Paula Moreira da Silva Sabaini, Rosana Rocha Concilio, Joaquim Gasparini, Bruna Letícia da Silva Santos Geraldo, Leonardo Jun Otuyama, Luiz Carlos da Costa Junior, Eliana Cristina Martins Miranda, Fernando Barroso Duarte, Beatrice Araújo Duarte, Marcelo C. Pasquini
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e367

  • Real-world outcomes of BCL2 inhibitor-based combination therapy in myelodysplastic syndrome and acute myeloid leukemia – Experience from a university hospital in northeastern Brazil

    Gustavo Mesquita de Oliveira, Emanuelly Thays Muniz Figueiredo Silva Vasconcelos, Maria Laura Fontoura Chagas Rocha, Felipe de Menezes Cunha, Hercules Amorim Mota Segundo, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e315

  • Frailty score analysis of multiple myeloma patients in the evaluation prior to autologous hematopoietic stem cell transplantation

    Felipe de Menezes Cunha, Hércules Amorim Mota Segundo, Livia Andrade Gurgel, Lucas Freire Castelo, Natalia Costa Bezerra Freire, João Paulo de Vasconcelos Leitão, Beatriz Stela Gomes de Souza Pitombeira Araujo, Karine Sampaio Nunes Barroso, Gustavo Mesquita de Oliveira, Maria Laura Fontoura Chagas Rocha, Emanuelly Thays Muniz Figueiredo Silva Vasconcelos, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e316

  • Hematopoietic cell transplantation outcomes in public centers in Brazil: analysis of the Brazilian Registry of Hematopoietic Cell Transplantation and Cellular Therapy, 2012–2024

    Anderson João Simione, Cinthya Corrêa da Silva, Nelson Hamerschlak, Afonso Celso Vigorito, Heliz Regina Alves das Neves, Adriana Seber, Carmem Maria Sales Bonfim Bonfim, Vergilio Antonio Rensi Colturato, Samir Kanaan Nabhan, Vanderson Geraldo Rocha, George Maurício Navarro Barros, Decio Lerner, Liane Esteves Daudt, Juliana Folloni Fernandes, Marcos Paulo Colella, Alexandre Silvério, Rodolfo Daniel de Almeida Soares, Gustavo Machado Teixeira, Victor Gottardello Zecchin, Abrahão Elias Hallack Neto, Rony Schaffel, Rodolfo Froes Calixto, Simone de Castro Resende Franco, Gianne Donato Costa Veloso, Vaneuza Araújo Moreira Funke, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e317

  • Challenges in the management of patients with chronic myelomonocytic leukemia in the Brazilian public healthcare system: from diagnosis to transplantation

    Emanuelly Thays Muniz Figueiredo Silva Vasconcelos, Felipe de Menezes Cunha, Gustavo Mesquita de Oliveira, Maria Laura Fontoura Chagas Rocha, Hércules Amorim Mota Segundo, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e318

  • Occupational therapy in hospital playroom for children with Fanconi anemia undergoing hematopoietic stem cell transplantation

    Melissa Quitério Xavier, Dayane Regina dos Santos
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e326

  • Global expert perspectives on the future of hematopoietic cell transplantation and cell therapies

    Danielli Oliveira, Bernardo Cabral, Roseli Monteiro, Carlos Conte Filho, Pamela Lopes, Inara Amorim, Daniel Silva, Islaine Santana, Marcela Bhering
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e342

Short communication

Protocols of conduct

Case reports

  • Acute liver failure as an initial presentation of multiple myeloma

    Naddya Olivero Danies, Martin Milanesio, Ana Victoria Sanchez, Julieta Olmedo, Gaston Caeiro, Ana Lisa Basquiera
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e344

  • Hematopoietic stem cell transplantation in an adult patient with primary hemophagocytic lymphohistiocytosis

    Sthephanie de Lima Zielak, Simone Cunha Maradei, Tiago de Oliveira Boechat
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e347

  • Prenatal molecular diagnosis and allogeneic hematopoietic stem cell transplantation in an infant with RAG2 deficiency

    Maria Laura Herrera Andino, Milagros López Orozco, María Victoria Suen, Carlos Hernán Hollmann, Lucía Spossito, Arjan Lankester, María Emilia Mas, Ana Lisa Basquiera
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e370

  • Post-transplantation cyclophosphamide-based graft-versus-host disease prophylaxis in a patient transplanted from a matched related but non-sibling donor

    Kazutoshi Ebisawa, Takahiro Takeuchi
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e320

  • Clonal histiocytosis associated with evolving acute myeloid leukemia: a case report and literature review

    Maria Laura Rocha, Emanuelly Thays Muniz Figueiredo Silva Vasconcelos, Gustavo Mesquita de Oliveira, Felipe de Menezes Cunha, Karla Hauanna Almeida Chaves do Vale, Francisco Dário Rocha Filho, Fernando Barroso Duarte
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e323

  • Allogeneic hematopoietic stem cell transplantation in patients with sickle cell disease with alternative donors – Case series

    Marlene Micaela Sepich, Milagros Lopez Orozco, Gonzalo Ariel Ferini, Martin Milanesio, Maria Emilia Mas, Jorge Alberto Arbelbide, Ana Lisa Basquiera
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e313

  • Oral pyogenic granulomas: a rare manifestation of oral graft-versus-host-disease

    Maria Julia Pagliarone, Thiago Carvalho Reis, Giovana Dornelas Azevedo Romero, Tatiane Cristina Ferrari, Carlos Eduardo Settani Grecco, Luiz Guilherme Darrigo Junior, Joana Teresa Bisinella de Faria, Rodrigo Braz Campos, Thalita Cristina de Mello Costa, Ana Beatriz Pereira Lima Stracieri; Lara Maria Alencar Ramos Innocentini; Hilton Marcos Alves Ricz; Leandro Dorigan de Macedo
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e331

Cellular Therapy Manual

  • CAR-T cells and other cellular therapies for solid tumors: Current challenges and emerging solutions

    Izadora Peter Furtado, Karolina Santos Esteves, Lucas Eduardo Botelho de Souza
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e358

  • Regulatory and operational framework for Chimeric Antigen Receptor T cell therapy in Brazil

    Andrea Kondo, Felipe Mesquita, Léo Sekine, Marília Maia, Nelson Hamerschlak
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e343

  • Natural killer cell biology

    Annelise Pezzi, Vanessa Valim, Bruna Amorin, Bruna Zambonato, Aline Paz, Juliana Furlan, Marcelo Teixeira, Davi Martins, Michelle Flores Domingues , Raul Marques Rodrigues, Fabiane Spagnol, Juliana Nóbrega Trzesniak, Leo Sekine, Lucia Silla
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e366

  • Genetic engineering strategies for cell-based therapy: viral, non-viral, and precision genome editing technologies

    Wing Keung Chan, Marcos de Lima
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e327

  • Neurological complications in patients receiving CAR T-cell therapies

    Justin Jiang, Virginia Battistin, Marcos de Lima, Francesca Cottini
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e324

  • Lymphocyte collection for cellular therapy

    Sérgio Luiz Arruda Parente Filho, Suzanna Tavares Barbosa, Naliele Cristina Maia de Castro, Araci Sakashita
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e330

  • What does the pharmacist need to know?

    Daniella Cristina Oliveira, Jenifer Freitas da Silva
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e334

  • Chimeric antigen receptor-natural killer

    Larissa Cardoso Zanetti, Raquel de Melo Alves Paiva, Lucila Nassif Kerbauy
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e335

  • Manufacturing of CAR-T cells using in-house vectors and the CliniMACS Prodigy

    Lucila Nassif Kerbauy, Felipe Pantoja Mesquita
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e338

Adult Consensus Updates

  • Consensus on graft-versus-host disease

    Vaneuza Funke, João Victor Feliciano, Giancarlo Fatobene, Maria Cláudia Moreira, Antonio Vaz de Macedo, Rita de Cássia Barbosa da Silva Tavares, Marcia de Matos Silva, Marcos Paulo Colella, Morgani Rodrigues, Luis Fernando da Silva Bouzas, Afonso Celso Vigorito
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e361

  • Recommendations for the prevention, monitoring, and treatment of infectious complications post-hematopoietic cell transplantation

    Marcia Garnica, Fabianne Carlesse, Jessica Fernandes Ramos, Ana Verena Almeida Mendes, Larissa Gandolpho, Giovanni Luis Breda, Marcio Nucci, Clarisse Martins Machado
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e352

  • Sinusoidal obstruction syndrome

    Fernanda Ribeiro Santos, Marco Salvino, Roselene Mesquita Augusto Passos, Luiz Henrique Assis, Natalia Maria Tavares Ferreira Borges, Nelson Hamerschlak, Eduardo José de Alencar Paton
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e357

  • Beyond HLA matching: a practical framework for selecting among HLA-identical donors in hematopoietic stem cell transplantation

    Simone Cunha Maradei, Mariana Torres Mazzi, Clara Werner Rosemberg, Luiz Fernando Bouzas
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e359

  • Hematopoietic progenitor cell mobilization, collection, transportation, and infusion of fresh products

    Karen Lima Prata, Andrea Tiemi Kondo, Karine Sampaio Nunes Barroso, Aline Miranda de Souza, Andreza Alice Feitosa Ribeiro
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e362

  • Brazilian Guidelines for Ocular Graft-versus-Host Disease After Hematopoietic Stem Cell Transplantation: Recommendations from the Brazilian Society of Bone Marrow Transplantation

    Marilia Trindade, Monica Alves
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e365

  • Donor selection: Histocompatibility and immunogenetics

    Alberto Cardoso Martins Lima, Danielli Cristina Muniz de Oliveira, Gisele Fabianne Rampim, Raquel Aparecida Fabreti-Oliveira, Margareth Afonso Torres
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e369

  • Hematopoietic stem cell transplantation for acute myeloid leukemia: Brazilian Society of Cell Therapy and Bone Marrow Transplantation Consensus

    Mariana Pereira, Maura Rosane Valério Ikoma-Colturato, Vaneuza Araujo Funke, Beatriz Stela Gomes de Souza Pitombeira, Eduardo José de Alencar Paton, Adriano Arantes, Karine Sampaio Nunes Barroso, Miriam Perlingeiro Beltrame, Gustavo Bettarello, Camila de Pádua Coelho Hugo, Tharsis Cardoso Ferreira dos Santos, Felipe Magalhães Furtado, Elizabeth Xisto Souto, Fernando Barroso Duarte, Lucia Silla
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e373

  • Brazilian guidelines for oral graft-versus-host disease: Recommendations from the Brazilian Society of Bone Marrow Transplantation

    Leandro Dorigan de Macedo, Mariana Andrade Costa, Fernanda de Paula Eduardo, Leticia Mello Bezinelli, Paulo Sergio da Silva Santos, Heliton Spíndola Antunes, Maria Elvira Pizzigatti Correa
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e380

  • Hematopoietic cell transplantation for myelodysplastic syndromes

    Fernando Barroso Duarte, Yhasmine Delles Oliveira Garcia, Karine Sampaio Nunes Barroso, Roberto Luiz da Silva, Lívia Andrade Gurgel, João Paulo de Vasconcelos Leitão, Beatriz Stela Gomes de Souza Pitombeira, Rodolfo Daniel de Almeida Soares, Gustavo Bettarello
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e350

  • Hematopoietic stem cell transplantation for hemoglobinopathies in adults

    Thalita Cristina de Mello Costa, Adriana Seber, George Maurício Navarro Barros, João Victor Piccolo Feliciano, Roseane Vasconcelos Gouveia, Cíntia Delbem Albino, Ricardo Helman, Gil Cunha De Santis, Vanderson Rocha, Belinda Pinto Simões
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e355

  • Gynecological chronic graft-versus-host disease: screening, diagnosis, and treatment. Brazilian Society of Cell Therapy and Bone Marrow Transplantation consensus

    Lenira Maria Queiroz Mauad, Andrea Maria Novaes Machado
    DOI: https://doi.org/10.46765/2675-374X.2025v7n1e340